department
of anatomy
roose
lab

welcome

Our goal is to understand how different flavors of receptor triggered Ras signals drive normal developmental processes of various cell types and organ systems and how (and why) perturbations of Ras-kinase signals cause human disease.

We take a very collaborate approach and integrate different research disciplines into our research program. We study cell-cell communication with biochemical assays in cell lines, with mouse models, and with organoids from patient samples. We strive to obtain entirely new insights into the mechanisms that underlie autoimmune diseases, leukemia, carcinomas, and COVID-19.
latest news
2020
JULY
  • Large collaborative program on metastatic
2020
JUNE
  • Kayla’s STAR Protocols accepted
2020
MAY
  • COVID-19 supplement granted
2020
March
  • Damia’s STAR Protocols accepted
2020
MARCH
  • Readjusting to “Shelter in place” in CA
2020
JANUARY
  • Lisiena, Kriti, and Rita all join the lab
2019
NOVEMBER
  • Organoid D2B is ramping up organoid production
2019
OCTOBER
  • Collaboration with the Kuriyan lab in Science
We are grateful for the financial support from the following agencies:
  • NIH/NIAID (P01 Program Project - AI091580)
  • NIH/NIAID (R01 - AI104789)
  • NIH/NCI (R01 - CA187318)
  • NIH/NHLBI (R01 - HL120724)
  • Mark Foundation for Cancer Research (Momentum Fellow)
  • ImmunoX CoProject Funds
  • COVID-19 Administrative Supplement
  • Mark Foundation for Cancer Research (Endeavor Award)