department
of anatomy
roose
lab

welcome

Our goal is to understand how different flavors of receptor triggered Ras signals drive normal developmental processes of various cell types and organ systems and how (and why) perturbations of Ras-kinase signals cause human disease.

We take a very collaborate approach and integrate different research disciplines into our research program. By bridging biophysical-, computational-, and novel technological- approaches with our biochemical investigations of cell lines, mouse models, and patient samples, we strive to obtain entirely new insights into the mechanisms that underlie autoimmune diseases, leukemia, and carcinomas.
latest news
2018
October
2018
september
2018
july
2018
june
  • Jesse’s paper in Science Signaling!
2018
April
  • Darienne scores cool job at Revolution Medicines!
  • Jesse scores cool job at Gilead!
2018
March
  • Darienne wins iBiology competition
  • Kayla joins the lab!
2018
February
  • Olga’s paper in PlosONE!
2018
January
  • Saikat becomes a IRACDA Scholar!
2017
september
  • Yvonne’s story in eLIFE!
2017
august
  • Catherine - Immunology training grant!
2017
July
  • Darienne in Trends in Immunology!
2017
may
  • Darienne & Tannia in Cell Report!
We are grateful for the financial support from the following agencies:
  • NIH/NIAID (P01 Program Project - AI091580)
  • NIH/NIAID (R01 - AI104789)
  • NIH/NCI (R01 - CA187318)
  • NIH/NHLBI (R01 - HL120724)
  • Mark Foundation for Cancer Research
  • UCSF PBBR TMC grant
  • Marcus Program in Precision Medicine Innovation
Additional:
  • NIH (F31 - CA200342)
  • NIH/NIAID (T32 - postdoc training grant slot)
  • Rothschild Postdoctoral Fellowship in the Natural, Exact or Life Sciences and Engineering
  • Fellowship Program Outstanding postdoctoral researchers from the Arab Sector
  • UCSF IRACDA Program (K12GM081266)